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Valentine B Andela Selected Research

AGN 193109

3/2004The proteosome inhibitor MG132 attenuates retinoic acid receptor trans-activation and enhances trans-repression of nuclear factor kappaB. Potential relevance to chemo-preventive interventions with retinoids.

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Valentine B Andela Research Topics

Disease

6Neoplasms (Cancer)
12/2005 - 04/2002
3Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar)
12/2005 - 10/2003
3Neoplasm Metastasis (Metastasis)
10/2003 - 04/2002
2Prostatic Neoplasms (Prostate Cancer)
04/2004 - 10/2003
1Ovarian Neoplasms (Ovarian Cancer)
04/2004
1Adenocarcinoma
10/2003

Drug/Important Bio-Agent (IBA)

2Mevalonic Acid (Mevalonate)IBA
04/2004 - 10/2003
2Alendronate (Alendronate Sodium)FDA LinkGeneric
04/2004 - 10/2003
2Tretinoin (Retinoic Acid)FDA LinkGeneric
03/2004 - 05/2003
2Proteins (Proteins, Gene)FDA Link
10/2003 - 04/2002
1NF-kappa B (NF-kB)IBA
12/2005
1Fatty Acid Synthases (Fatty Acid Synthase)IBA
03/2005
1Troglitazone (Rezulin)FDA Link
03/2005
1EnzymesIBA
03/2005
1Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA
03/2005
1Hydroxymethylglutaryl-CoA SynthaseIBA
03/2005
1PPAR gammaIBA
03/2005
1lysophosphatidic acidIBA
04/2004
1AGN 193109IBA
03/2004
1mevastatin (CS 500)IBA
10/2003
1Transcription Factors (Transcription Factor)IBA
10/2003
1RetinoidsIBA
05/2003
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
05/2003
1Metalloproteases (Metalloproteinases)IBA
05/2003
1TransferasesIBA
04/2002

Therapy/Procedure

2Therapeutics
12/2005 - 10/2003